发表时间:2019-07-10
(1) Magnesium sulfate can inhibit the central nervous system and relax skeletal muscle. It has the functions of sedation, anti-spasm and reducing intracranial pressure. It is often used to treat convulsions, eclampsia, uremia, tetanus and hypertensive encephalopathy. 10% magnesium sulfate 10 ml deep intramuscular injection or 5% glucose diluted into 2%-2.5% solution slowly drip. However, it should be noted that direct intravenous injection or high dose intramuscular injection of magnesium sulfate is very dangerous. Generally, 25% magnesium sulfate can be used up to 15 ml at a time. The breathing and blood pressure of patients should be observed carefully when using, and knee reflex retardation is an important sign of magnesium ion adequacy.
(2) Magnesium plays an extremely important role in the metabolism of sugar and protein. Magnesium salts should be supplemented to children during growth and development if they have indigestion and when vitamin D is used.
(3) Magnesium has many physiological functions similar to potassium. Because the clinical manifestations of magnesium deficiency are similar to those of potassium deficiency, magnesium deficiency is often neglected. When the symptoms of hypomagnesemia are not improved after potassium supplementation, the possibility of magnesium deficiency should be considered first, so that hypomagnesemia can be corrected in time. Therefore, long-term infusion patients should pay attention to magnesium supplementation while potassium supplementation. The hypomagnesemia can be prevented by adding 1 gram of magnesium sulfate to the infusion every day.
(4) When digitalis is used in patients with cardiac insufficiency, magnesium salts can be supplemented properly to prevent low magnesium from aggravating the toxicity of digitalis. Magnesium salts are often effective in the treatment of tachycardia.
(5) Oral magnesium sulfate is rarely absorbed in the intestinal tract, so it is not used for the above purposes. But oral magnesium sulfate has good cathartic function, so magnesium sulfate is also called cathartic salt. When the oral magnesium sulfate solution reaches the intestinal cavity, it has a certain osmotic pressure, so that the intestinal water can not be absorbed by the intestinal wall. The intestine retains a large amount of water, which can mechanically stimulate intestinal peristalsis and defecate. Therefore, magnesium sulfate can be used to treat constipation and abnormal intestinal fermentation, and when combined with insecticide repellent, intestinal worms can be easily discharged. It can dissolve 5-20 grams of magnesium sulfate in 100-400 ml boiling water at a time, and take it orally in the morning. Concentration is not easy to be too high, 5% is the best, otherwise defecation will be delayed.
(6) Magnesium sulfate can stimulate duodenal mucosa, reflexively cause the relaxation of common bile duct sphincter and gallbladder contraction, thus promoting gallbladder emptying, which is beneficial to gallbladder. It can be used to treat cholecystitis and cholelithiasis, 2-5 grams each time, 3 times a day, before meals or between meals. 50% magnesium sulfate diluted to 33% (high concentration), 5 ml Tid.
(7) Magnesium sulfate can be used for digestive tract radiography
(8) Anti-inflammation and anti-swelling 50% solution for external hot compress on the affected area, has anti-inflammation and anti-swelling effect.
Magnesium sulfate powder external application can reduce swelling, used to treat swelling after extremity injury, help improve rough skin, etc.
Magnesium sulfate is easily soluble in water and not absorbed by oral administration. Magnesium ion and sulfate ion in aqueous solution are not easily absorbed by intestinal wall, which increases intestinal osmotic pressure, moves water from body fluid to intestinal cavity, increases the volume of intestinal cavity and dilates intestinal wall, thus stimulating the afferent nerve endings of intestinal wall, and reflexively causes intestinal peristalsis and diarrhea. It acts on all intestinal segments, so it acts quickly and strongly. As cathartic and duodenal drainage agent.
Magnesium sulfate intravenous injection and intramuscular injection are mainly used for anti-convulsion, which can cause vasodilation and decrease blood pressure. Because of its central inhibitory effect and skeletal muscle relaxation, it is mainly used for relieving eclampsia, tetanus and other convulsions, and also for the treatment of hypertension crisis. It is also used as a poison for barium salts.